|It is believed that telomere length is one of the principal clocks that are aging of the body.But herbal telomerase activators that are available now are weak enough to stop the ongoing decline of telomere length with age. We can hope that in the future, designer molecules will do better than the best herbs of today.Are the herbs successful enough to be worth anything in any way? The very small clinical and laboratory data that we’ve suggests that they are doing more for us than we had any right to expect. This really is extremely promising.The best information that we have on telomerase activation is for a product called TA-65, sold by TA Sciences in New York. This company has financed nearly all of the research, illustratingthat TA-65 works to slow shortening of the shortest (most dangerous) telomeres in the human body
that TA-65 added to food improves well-being and lengthens life span in mice with no increase in cancer incidence
TA-65 is widely rumored to be cyclo- a touch ingredient in the Chinese herb Astragalus, astragenol.
No corresponding data is available for any other material -astragenol. Cyclo astragenol is available from other firms for a fraction of the cost of TA-65.
Though TA-65 is the sole product for which there’s animal and human data, it might be that it is not the best telomerase activator. In cell cultures, several herbs are much more powerful than TA-65. In doing these cell culture assays for telomerase activity, leader is Sierra Sciences in Reno, NV. Sierra licensed a mixture of the utmost effective herbs seen in their wide-ranging tests and has designed. This is sold as Product B by Isagenix. All kidding aside, horny goat weed was used as an aphrodisiac in the Orient for centuries, which might or might not be what you want in an anti-aging supplement. Active ingredient is believed to be icariin.
The herbs that consist of Product B are available individually from several suppliers, at less in relation to the expense of Product B.
Carnosine is a “minimalist” protein, consisting of only two amino acids. It’s seen in human cells that were youthful, but we have much less as we age. Carnosine impedes the loss of telomeres in human cell cultures, too as appearing to decrease the telomere shortening speed.
In animal models carnosine has been shown to retard cancer growth and protect against alcohol-induced oxidative stress as well as ethanol-induced long-term liver damage. Carnosine has shown potential as a neuroprotective agent as well. It prolongs life span in flies, and there’s one study (1999) on a specific breed of mice that yielded tentatively favorable results. Expanding and replicating that study should be a high priority, if there is a rationality in the universe of science funding.
Carnosine is best used on an empty stomach. I really believe that telomere length is one of the body’s primary clocks that are aging. Lengthening telomeres is the most promising avenue toward life extension.